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Predicting intrahepatic recurrence of colorectal cancer liver metastases after curative hepatectomy using a machine learning model with data integration of ultrasound radiomics and clinicopathological

4 hours ago
  • #radiomics
  • #colorectal cancer
  • #machine learning
  • A machine learning model was developed to predict intrahepatic recurrence in colorectal cancer liver metastases (CRLM) patients post-hepatectomy.
  • The study included 278 patients from two centers, divided into a main cohort (n=224) and an external cohort (n=54).
  • Models developed: clinical, radiomics, and a combined clinical-radiomics (cRadiomics) model.
  • Key predictors included six clinical parameters and seven radiomics features.
  • The cRadiomics model outperformed others with AUC values of 0.811 (main cohort) and 0.784 (external cohort).
  • The model aims to improve clinical decision-making and personalized management for CRLM patients.