Diagnosis of Functional Dyspepsia and Novel Gastrointestinal Functional Assessments - PubMed
4 days ago
- #Gut-Brain Axis
- #Gastrointestinal Assessment
- #Functional Dyspepsia
- Functional dyspepsia (FD) is a common gut-brain disorder causing postprandial distress and epigastric pain, impacting quality of life and healthcare burden.
- Diagnosis traditionally relies on clinical history and exclusion of organic diseases, but lacks insight into underlying mechanisms.
- Recent advances include detailed assessments of gastric accommodation, emptying, motility, and sensory function using techniques like barostat, antroduodenal manometry, and gastric scintigraphy.
- Emerging noninvasive methods such as cine MRI, body surface gastric mapping, and wireless motility capsules offer comprehensive insights into gastric function.
- Endoscopy-based functional testing and autonomic nervous system assessments (e.g., heart rate variability) enhance understanding of FD's gut-brain axis.
- Despite progress, standardization and wider clinical adoption of these tools are needed for personalized FD management.