The combined estimated glucose disposal rate and frailty index predicts cardiovascular events and mortality: A prospective cohort study from CHARLS - PubMed
6 hours ago
- #mortality prediction
- #frailty index
- #cardiovascular disease
- The study introduces a composite index, eGDRFI, which combines the estimated glucose disposal rate (eGDR) and frailty index (FI) to predict cardiovascular events and mortality.
- Each 1-unit increase in eGDRFI significantly raises the risk of cardiovascular disease and all-cause mortality, with the highest quartile showing markedly elevated hazard ratios compared to the lowest quartile.
- eGDRFI demonstrates higher discriminative ability in predicting incident cardiovascular disease and all-cause mortality compared to using eGDR or FI alone, as shown by ROC curve analysis.
- The findings suggest that eGDRFI could serve as a practical tool for risk stratification in middle-aged and older adults based on data from the CHARLS cohort.