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Clinical Impact of Diabetes Mellitus After Intravascular Imaging-Guided PCI vs Coronary Artery Bypass Grafting - PubMed

7 hours ago
  • #Coronary Artery Disease
  • #Percutaneous Coronary Intervention
  • #Diabetes Mellitus
  • CABG is the standard revascularization method for DM patients with complex coronary artery disease.
  • The study compares clinical outcomes of IVI-guided PCI, angiography-guided PCI, and CABG in DM patients with left main or 3-vessel disease.
  • 3,402 DM patients were included from the RENOVATE-COMPLEX-PCI trial and Samsung Medical Center registries.
  • Primary outcome was a composite of all-cause death, nonfatal myocardial infarction, or stroke at 3 years.
  • 3-year primary outcome incidence: 20.1% for angiography-guided PCI, 11.4% for IVI-guided PCI, and 12.4% for CABG.
  • PCI had higher risk for primary outcome compared to CABG (17.0% vs 12.4%).
  • IVI-guided PCI had comparable risk to CABG (11.4% vs 12.4%).
  • Propensity score-matched analysis confirmed similar results between IVI-guided PCI and CABG.
  • Further randomized controlled trials are needed to confirm findings.