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Prevalence and incidence of depressive, anxiety, and insomnia symptoms in perimenopausal and postmenopausal women: Systematic review and meta-analysis - PubMed

4 hours ago
  • #menopausal mental health
  • #depression anxiety insomnia
  • #systematic review meta-analysis
  • Systematic review and meta-analysis of 102 studies (N=1,141,955) synthesizes prevalence and incidence of depressive, anxiety, and insomnia symptoms in perimenopausal and postmenopausal women.
  • Pooled point prevalence of depressive symptoms is 32% in perimenopausal and 30% in postmenopausal women; period prevalence is lower at 24% and 19%, respectively.
  • Incidence rates for depressive symptoms are 13% in perimenopausal and 5% in postmenopausal women.
  • Anxiety point prevalence is 29% in perimenopausal and 39% in postmenopausal women.
  • Insomnia point prevalence is higher in postmenopausal women (42%) compared to perimenopausal women (27%).
  • Subgroup analyses show higher symptom rates when using screening instruments and during early menopause stages.
  • Most studies had low or moderate risk of bias, supporting the reliability of the pooled estimates.
  • Conclusions highlight that nearly one in three women experiences these symptoms during menopausal transition, advocating for routine mental health screening and integrated care.