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Ion channels in macrophages: dynamic regulation in cardiovascular and cerebrovascular diseases and therapeutic potential - PubMed

4 hours ago
  • #Ion channels
  • #Macrophages
  • #Cardiovascular diseases
  • Cardiovascular and cerebrovascular diseases (CCVDs) are a major global health challenge.
  • Macrophages play a critical role in maintaining and remodeling CCVD homeostasis.
  • Ion channels in macrophages influence immune responses and inflammatory processes.
  • This review explores the expression and functional regulation of macrophage ion channels in CCVDs.
  • Discusses the heterogeneity of ion channels across different macrophage subsets.
  • Analyzes the mechanistic roles of ion channels in CCVD progression and repair.
  • Highlights the therapeutic potential of targeting macrophage ion channels for CCVDs.