Targeting Epstein-Barr virus (EBV) for treatment of multiple sclerosis - PubMed
3 hours ago
- #Autoimmune Disease
- #Multiple Sclerosis
- #Epstein-Barr Virus
- Epstein-Barr Virus (EBV) is a key causal agent in Multiple Sclerosis (MS).
- MS is a chronic autoimmune disease causing demyelination and neurodegeneration in the CNS.
- EBV establishes long-term latent infection in memory B-lymphocytes.
- EBV-infected B-lymphocytes drive MS pathogenesis, though the exact mechanism is unclear.
- EBV is also implicated in other diseases, including cancers.
- Conditions and cofactors increasing MS risk post-EBV infection are discussed.
- Potential treatments include pharmacological, biologic, and vaccine approaches targeting EBV.