Impact of Procedural Quality on Outcomes of Transarterial Chemoembolization for Hepatocellular Carcinoma: A Multicenter Study - PubMed
3 hours ago
- #hepatocellular carcinoma
- #transarterial chemoembolization
- #procedure quality
- TACE is a primary treatment for intermediate-stage HCC, but outcomes vary due to lack of standardization.
- A multicenter study of 3,059 HCC patients compared precision TACE (adhering to technical criteria) with non-precision TACE.
- Precision TACE showed higher first objective response rate (59.4% vs. 47.0%) and overall ORR (70.6% vs. 59.8%).
- Precision TACE also led to better progression-free survival (median 14.00 vs. 10.80 months) and overall survival (median 33.63 vs. 26.37 months).
- A quality scoring system correlated procedural quality with treatment response, and precision TACE had lower hepatobiliary toxicity rates.
- The study concludes that precision TACE improves outcomes and safety, suggesting the scoring system as a quality assessment tool.