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One year of seizure freedom reduces premature death in people with epilepsy in rural China: A 10-year cohort study - PubMed

4 hours ago
  • #seizure freedom
  • #mortality
  • #epilepsy
  • One year of seizure freedom reduces premature death in people with epilepsy in rural China.
  • The study followed 610 participants over 10 years, with 67 deaths recorded.
  • Epilepsy-related deaths accounted for 48% of deaths, with sudden unexpected death in epilepsy being predominant (33%).
  • People who achieved 12-month seizure freedom had significantly lower standardized mortality ratios (SMRs).
  • Achieving seizure freedom was independently associated with a lower risk of all-cause mortality and epilepsy-related death.
  • The protective effect of seizure freedom was most pronounced in women, older adults, those with seizure onset during adulthood, and those without comorbidities.
  • Mortality in the cohort was more than twice that of the general population.
  • Seizure control is highlighted as a practical and encouraging treatment goal in resource-limited settings.