Therapeutic Plasma Exchange for Uncontrollable Bleeding After Platelet Inhibition with Ticagrelor: A Report of 2 Cases - PubMed
3 hours ago
- #Therapeutic Plasma Exchange
- #Ticagrelor
- #Uncontrollable Bleeding
- Therapeutic Plasma Exchange (TPE) was used to manage uncontrollable bleeding caused by ticagrelor in two cases.
- Case 1: A 52-year-old man with ST-elevation myocardial infarction experienced uncontrolled bleeding post-surgery, which was controlled after TPE.
- Case 2: A 66-year-old man had uncontrolled bleeding after PCI and bypass surgery; TPE stabilized bleeding and improved platelet reactivity.
- TPE effectively removed circulating ticagrelor, achieving hemostasis and reducing the need for further blood products.
- TPE is suggested as a novel emergency treatment for refractory bleeding due to ticagrelor.