From brain waves to heartbeats: Exploring the combined role of electroencephalography and heart-rate variability in Alzheimer's disease diagnosis and management - PubMed
7 hours ago
- #Alzheimer's disease
- #neurovisceral decline
- #EEG-HRV coupling
- Alzheimer's disease (AD) impacts memory, cognition, and autonomic functions like heart rate and blood pressure.
- EEG measures brain activity, showing cortical slowing, while HRV reflects heart response flexibility.
- Combined EEG-HRV coupling improves accuracy in diagnosing mild cognitive impairment and early AD compared to individual measures.
- Neurovisceral decline in AD is marked by loss of coordination between neural and autonomic systems.
- Methodological gaps include inconsistent recording conditions and lack of standardized analysis methods.
- A translational roadmap is proposed for clinical validation, wearable integration, and digital health applications.
- EEG-HRV coupling is a non-invasive, scalable tool for earlier and personalized AD monitoring.