Immunosenescence and susceptibility to respiratory viruses: a state-of-the-art review - PubMed
7 hours ago
- #ageing
- #immunosenescence
- #respiratory viruses
- The global rise in the older population presents new challenges for healthcare systems.
- Ageing is linked to immunosenescence (immune system decline) and inflammageing (chronic low-grade inflammation), increasing susceptibility to infections.
- Older adults face higher morbidity and mortality from respiratory viral infections due to these immune changes.
- The review explores molecular and cellular mechanisms behind immunosenescence and inflammageing.
- Clinical implications, biomarkers, preventative measures, and treatments for mitigating immunosenescence effects are discussed.
- Funding and conflicts of interest are disclosed, including support from various health and research organizations.