Intra-Articular Injectable Hydrogel Microsphere-Based Drug Delivery System for Osteoarthritis Treatment - PubMed
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- #hydrogel-microspheres
- #drug-delivery
- #osteoarthritis
- Osteoarthritis (OA) is a chronic degenerative joint disease with increasing prevalence due to aging and obesity.
- Traditional OA therapies can only slow disease progression and have significant adverse effects.
- Hydrogel microsphere technology offers a novel therapeutic approach for OA treatment.
- Hydrogel microspheres can create a biomimetic microenvironment for cartilage regeneration and enable intelligent drug release.
- The review discusses changes in the joint microenvironment caused by OA and the properties required for effective hydrogel microspheres.
- Preparation methods, structural characteristics, and modification strategies of hydrogel microspheres are explored.
- Hydrogel microspheres serve as delivery systems, with current challenges and future perspectives highlighted.