Drug-Coated Balloon Angioplasty vs Drug-Eluting Stents in Noncomplex Coronary Bifurcation Lesions: The REC-CAGEFREE I Trial - PubMed
3 hours ago
- #interventional cardiology
- #clinical trial
- #coronary artery disease
- REC-CAGEFREE I trial compared drug-coated balloons (DCBs) to drug-eluting stents (DES) for treating noncomplex coronary lesions, including bifurcations.
- At 24 months, the device-oriented composite endpoint (DoCE) was similar between DCBs and DES for bifurcation lesions (6.7% vs 5.3%), but DCBs had higher DoCE than DES in nonbifurcation lesions (6.3% vs 2.4%).
- The interaction between lesion type (bifurcation vs nonbifurcation) and treatment was significant, suggesting DCB may be comparable to DES only for noncomplex bifurcations, though results are hypothesis-generating.