Influence of Neurovascular Conflict on the Outcome of Primary Gamma Knife Radiosurgery for Trigeminal Neuralgia: A Single-Center Retrospective Study - PubMed
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- #Neurovascular Conflict
- #Trigeminal Neuralgia
- #Gamma Knife Radiosurgery
- Gamma Knife Radiosurgery (GKRS) is an effective treatment for medically intractable trigeminal neuralgia (TN).
- The study evaluated whether neurovascular conflict (NVC) influences pain and sensory outcomes post-GKRS.
- 148 patients who underwent primary GKRS for TN between 2014-2024 were retrospectively reviewed.
- 89% of patients achieved significant pain relief (BNI grade IIIb or better).
- Pain recurrence occurred in 20% of patients, and 32% developed facial sensory disturbances.
- Estimated pain relief rates were 77% at 1 year, decreasing to 64% at 7 years.
- NVC presence/severity did not predict pain or sensory outcomes post-GKRS.
- Facial sensory disturbances were associated with long-term pain relief.