Xiao-Feng Xuan-Qiao decoction alleviates allergic rhinitis by inhibiting neutrophil extracellular trap formation - PubMed
3 hours ago
- #Allergic Rhinitis
- #Neutrophil Extracellular Traps
- #Traditional Chinese Medicine
- Xiao-Feng Xuan-Qiao (XF) decoction alleviates symptoms in allergic rhinitis (AR) models, reducing sneezing and nasal rubbing.
- XF lowers IgE levels and decreases infiltration of eosinophils, neutrophils, and mast cells in AR-induced mice.
- XF inhibits neutrophil extracellular trap (NETosis) formation by suppressing the TLR2-ERK-PKC signaling pathway and reducing reactive oxygen species production.
- The study suggests XF provides a novel theoretical foundation for treating AR, potentially avoiding issues from long-term corticosteroid use.