Energetic metabolism-regulatory glycopeptide hydrogel accelerates pressure ulcer wound repair - PubMed
4 hours ago
- #metabolic-regulation
- #glycopeptide-hydrogel
- #wound-healing
- Development of a multifunctional glycopeptide hydrogel (GMIgel) for pressure ulcer wound repair.
- GMIgel integrates antibacterial activity with mitochondrial metabolism modulation.
- The hydrogel eradicates bacterial infection and restores mitochondrial function.
- Promotes macrophage metabolic reprogramming and M2 phenotype polarization.
- In vivo, GMIgel clears MRSA, reduces inflammation, and enhances angiogenesis.
- Accelerates healing of infected pressure ulcers by approximately 20%.
- Offers a novel strategy for MRSA-infected pressure ulcer treatment.