KIM-1 in Advanced Papillary and Clear Cell Renal Cell Carcinoma - PubMed
4 hours ago
- #renal cell carcinoma
- #biomarker
- #immunotherapy
- KIM-1 levels were higher in papillary RCC (pRCC) compared to clear cell RCC (ccRCC) in metastatic disease.
- Reductions in KIM-1 levels occurred with systemic therapy in both ccRCC and pRCC.
- In pRCC, lower baseline KIM-1 levels were associated with better radiological response.
- In ccRCC, high baseline KIM-1 levels were linked to shorter overall survival.
- In ccRCC, an increase in KIM-1 during therapy correlated with worse progression-free and overall survival.