Adaptive ROS-Responsive Dual-Layered Hydrogel with Ginkgo Biloba-Derived Exosome-Like Nanovesicles for Diabetic Wound Healing - PubMed
a day ago
- #plant-derived exosomes
- #diabetic wound healing
- #ROS-responsive hydrogel
- Development of a multifunctional bilayer hydrogel system (Dual-Gel) for diabetic wound healing.
- Dual-Gel consists of two layers: Gel 1 with antibacterial properties and Gel 2 that degrades in response to ROS.
- Gel 1 releases ε-polylysine and copper ions to combat infection and generate bactericidal ROS.
- Gel 2 degrades in high ROS environments, releasing exosomes that promote cell proliferation and angiogenesis.
- The system dynamically responds to ROS levels in the wound, offering precise bioactive component release.
- Potential novel regulatory strategy for managing complex diabetic wounds.