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Hepatitis B Virus Exposure and Metabolic Dysfunction-Associated Steatotic Liver Disease in U.S. Adults: A Nationally Representative Analysis from NHANES 2017-2020 - PubMed

5 hours ago
  • #NHANES
  • #Hepatitis B Virus
  • #MASLD
  • Study investigates the association between Hepatitis B Virus (HBV) exposure and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in U.S. adults using NHANES 2017-2020 data.
  • HBV-exposed individuals showed lower MASLD prevalence (21.6% vs. 27.5%) and a persistent inverse association after adjustment (OR 0.57, 95% CI 0.40-0.81).
  • Findings suggest the need for further investigation into metabolic assessment in HBV-exposed populations.
  • The study utilized complex survey-weighted analyses on 6,342 adults, representing 181.71 million U.S. residents.
  • MASLD diagnosis required hepatic steatosis plus at least one cardiometabolic risk factor (CMRF).
  • Results were consistent across subgroups and confirmed through sensitivity analyses.