Global Trends in Endometriosis Burden, 1990-2021: A Sociodemographic Analysis Using GBD 2021 Data and Projections to 2036 - PubMed

4 hours ago

Endometriosis is a chronic inflammatory disorder causing pelvic pain and infertility, significantly impacting women's health globally.
The study used GBD 2021 data to analyze endometriosis burden from 1990-2021, focusing on ASPR, ASIR, EAPC, and DALY metrics.
Findings show a decline in age-standardized prevalence and incidence rates (-1.02% and -1.00% EAPC, respectively), but total cases and DALY rose due to population growth and aging.
Geographic disparities were evident, with higher burdens in low SDI regions, particularly East Asia, South Asia, and Southeast Asia.
Eastern Europe was the only region with a positive EAPC, indicating increasing burden.
Health inequality analysis showed narrowed absolute disparities but intensified relative inequality in middle- and high SDI regions.
Adolescents (15-19 years) were identified as a key target group for prevention and control efforts.
Projections to 2036 suggest a continued decline in standardized burden, but persistent gaps across SDI levels and pronounced relative inequality.
The study emphasizes the need for tailored strategies for high-burden and vulnerable groups, especially adolescents, and advancements in diagnostic and therapeutic technologies.

Hasty Briefsbeta