Recent Advances in Guillain-Barré Syndrome: Neurological Disorder, Pathophysiology, Diagnosis, Treatment, and Challenges - PubMed
4 hours ago
- #Neurology
- #Autoimmune Disorder
- #Immunotherapy
- Guillain-Barré syndrome (GBS) is a rare autoimmune disorder affecting the peripheral nervous system.
- Recent research highlights autoantibody-induced nerve injury and immune cell involvement in GBS pathophysiology.
- Advanced diagnostic tools like metabolomic profiling and high-resolution imaging aid in early detection and subtype differentiation.
- Current treatments include IVIg and plasma exchange, with ongoing research into complement inhibitors and cytokine-targeting therapies.
- Fluid biomarkers show promise for improved disease monitoring and prognosis.
- Further clinical trials are needed to translate research findings into clinical practice.