Technologies to measure and modulate protein subcellular localization - PubMed
5 hours ago
- #proteomics
- #protein localization
- #cell biology
- Technologies to measure and modulate protein subcellular localization are crucial for understanding cell behaviors.
- Recent advances include microscopy, mass spectrometry-based correlation profiling, and proximity labeling methods.
- Tools for manipulating protein localization include localization tags and bifunctional molecules.
- The review assesses the strengths and weaknesses of each technology.
- Future technological advances in spatial subcellular proteomics could impact cell biology and clinical applications.