Anti-Proliferative Effects of Resveratrol on Gingival Fibroblasts Derived From Amlodipine-Induced Gingival Overgrowth - PubMed
3 hours ago
- #Resveratrol
- #Gingival Overgrowth
- #Fibroblasts
- Resveratrol treatment significantly reduced cell proliferation in gingival fibroblasts from amlodipine-induced gingival overgrowth (GO) patients without cytotoxicity.
- Resveratrol decreased levels of fibrosis-related markers (TGF-β1, CTGF, COL-1, IL-6, TGM-2) and increased antioxidant SOD levels in the GO group.
- The study suggests resveratrol's potential therapeutic role in modulating extracellular matrix metabolism and oxidative stress in drug-induced gingival overgrowth.