Probiotic characterization and spore production optimization of Lysinibacillus sp. MK212927 - PubMed

4 days ago

Lysinibacillus sp. MK212927 shows strong antagonistic activity against human enteropathogens.
The strain exhibits high resilience under stress conditions like low pH, bile salts, and heat.
Safety evaluation confirmed no hemolytic activity and minimal cytotoxicity.
Response surface methodology (RSM) optimized biomass and spore production, increasing yields significantly.
In vivo tests showed improved body weight gain in rats, supporting its use as a feed supplement.
The strain has potential applications in animal and human nutrition as a probiotic.

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