Cystoscopic application of RADA16 peptide for refractory haematuria from radiation cystitis - PubMed
3 hours ago
- #refractory haematuria
- #RADA16 peptide
- #radiation cystitis
- RADA16 peptide was applied cystoscopically to treat refractory haematuria from radiation cystitis in 15 patients who did not respond to standard treatments.
- The procedure involved cystoscopy under general anaesthesia, CO2 insufflation of the bladder, application of RADA16 over radiation telangiectasia, and a 5-minute dwell time.
- At 6 weeks, 14 out of 15 patients showed significant reduction in bleeding; one required cystectomy, and two needed re-treatment within 3 months.
- Follow-up cystoscopies within 3 months indicated regression of radiation-induced telangiectasia without bladder scarring or ureteric obstruction.
- RADA16 application is noted as a promising novel treatment that provides haemostasis and promotes healing in radiation cystitis cases.