Serum IL-2 levels are associated with disease activity and related to dyslipidaemia and the immunological profile in systemic lupus erythematosus - PubMed
7 hours ago
- #Cardiovascular Diseases
- #Inflammation
- #Autoimmune Diseases
- Serum IL-2 levels are linked to disease activity in systemic lupus erythematosus (SLE).
- IL-2 is associated with inflammatory markers like C-reactive protein and IL-6.
- Disease activity, measured by SLEDAI-2K, positively correlates with IL-2 levels.
- Specific autoantibodies (anti-DNA, anti-SSA, anti-SSB, anti-Sm, antiribosome) show positive associations with IL-2.
- Triglycerides are positively associated with IL-2, while HDL-cholesterol shows an inverse relationship.
- The study highlights IL-2's role in SLE immunopathogenesis, linking inflammation and metabolic pathways.