Risk factors for ductal carcinoma in situ: comparisons with invasive breast cancer - PubMed
19 hours ago
- #Breast cancer risk factors
- #Ductal carcinoma in situ
- #Multiethnic cohort
- DCIS is a precursor to invasive breast cancer but does not always progress.
- Risk factors for DCIS include higher risk in African American, Native Hawaiian, and Japanese American women compared to White women.
- Family history of breast cancer, Type 2 diabetes, nulliparity, older age at first birth (>30), and current estrogen hormone therapy increase DCIS risk.
- Parity (having children) and non-U.S. birthplace decrease DCIS risk.
- Most risk factor associations are consistent across racial/ethnic groups, except smoking status shows increased risk only for Native Hawaiians.
- The study highlights shared and distinct risk factors between DCIS and invasive breast cancer, suggesting need for better risk stratification.