MR-ProADM Predicts Mortality and Heart Failure Events in ATTR Cardiac Amyloidosis - PubMed
8 hours ago
- #ATTR-CM
- #Prognosis
- #Biomarker
- MR-proADM is a strong predictor of mortality and heart failure events in ATTR cardiac amyloidosis, with a C-index of 0.788 for all-cause mortality.
- A threshold of MR-proADM ≥1.1 nmol/L was identified, improving mortality prediction when combined with existing staging systems.
- The findings were validated in two independent external cohorts, confirming the biomarker's prognostic value even in patients receiving tafamidis.