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Spread Through Air Spaces in Colorectal Lung Metastases Signals Local Recurrenece and Reflects Morphologic Aggressiveness of the Primary Tumor - PubMed

4 hours ago
  • #STAS
  • #Tumor Budding
  • #Pulmonary Metastases
  • STAS in colorectal lung metastases is associated with worse recurrence-free and overall survival, particularly intrathoracic recurrence.
  • Quantitative STAS metrics like density and spread distance correlate with intrathoracic recurrence risk.
  • High tumor budding grade in the primary tumor is linked to higher STAS presence and serves as a preoperative marker.