The association between inflammatory markers in routine blood counts at 1 year and attention-deficit/hyperactivity disorder (ADHD): A case-control study - PubMed
4 hours ago
- #biomarkers
- #ADHD
- #inflammation
- Study investigates the link between inflammatory markers in routine blood counts at age 1 and subsequent ADHD diagnosis.
- ADHD is a neurodevelopmental disorder with symptoms like inattention, hyperactivity, and impulsivity, possibly linked to immune-inflammatory processes.
- Retrospective case-control study used electronic medical records from Leumit Health Services (2006-2021), focusing on children with CBC tests at age 1.
- ADHD cases showed elevated WBC counts, including higher neutrophils, eosinophils, and lymphocytes, and lower basophils compared to controls.
- No significant differences were found in platelet-to-lymphocyte ratio (PLR) between ADHD and control groups.
- Findings suggest a preclinical inflammatory phenotype may be associated with ADHD risk, indicating early immune dysregulation as a potential factor.
- Early identification of inflammatory biomarkers could help in preventive strategies and targeted interventions for high-risk children.