hnRNPA1-SF3B3 interaction drives radioresistance in oral squamous cell carcinoma by modulating MARF1 alternative splicing isoforms - PubMed
4 hours ago
- #Radioresistance
- #Oral squamous cell carcinoma
- #Alternative splicing
- hnRNPA1-SF3B3 interaction contributes to radioresistance in oral squamous cell carcinoma by influencing MARF1 alternative splicing isoforms.
- The study utilized tissue microarrays from 60 OSCC patients and 18 biopsy samples from patients undergoing radical radiotherapy, with ethical approvals obtained.
- No competing interests were declared by the authors.
- References include studies on PSMA2, Tetrahedral-DNA-Nanostructure-Modified Engineered Extracellular Vesicles, non-operative management, partial vs. whole tumor-volume irradiation, and postoperative radiotherapy comparisons.
- Funding was provided by the National Natural Science Foundation of China and the Natural Science Foundation of Chongqing City.