Factors Associated With Self-Medication to Mitigate Vaccine Reactions After COVID-19 Vaccination: A Prospective Cohort Study - PubMed
6 hours ago
- #Vaccine Reactions
- #Nocebo Effect
- #Self-Medication
- About one-third of adults in a German study self-medicated with analgesics/antipyretics after their second COVID-19 mRNA vaccination.
- Self-medication was most common on the first day after vaccination, with NSAIDs and paracetamol being the most frequently used substances.
- Factors increasing self-medication included premedication use, receiving the mRNA-1273 (Moderna) vaccine, female gender, prior vaccine reaction experiences, expectations of reactions, and having chronic conditions.
- Higher satisfaction with the vaccination process was associated with lower rates of self-medication.
- Findings suggest nocebo effects may contribute to self-medication practices, and identifying these factors could help tailor pre-vaccination advice.