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Effect of Probiotic and Synbiotic Oral Supplementation in Autoimmune Diseases: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials - PubMed

3 hours ago
  • #Autoimmune Diseases
  • #Inflammation
  • #Probiotics
  • Probiotic supplementation reduces inflammatory markers (IL-6, IL-10, TNFα, hs-CRP) in autoimmune diseases.
  • Subgroup analysis shows benefits: rheumatoid arthritis patients improved in IL-6, IL-1β, TNFα; multiple sclerosis patients improved in hs-CRP.
  • The review includes 12 randomized controlled trials with 703 patients, highlighting probiotics as potential adjunctive therapy.
  • Further long-term studies are needed to confirm and explore lasting benefits of probiotics for autoimmune conditions.