The association between early-life respiratory infections and childhood asthma: a meta-analytic perspective - PubMed
4 hours ago
- #respiratory infections
- #childhood asthma
- #meta-analysis
- Early-life respiratory infections are strongly associated with childhood asthma and wheeze.
- Maternal influenza vaccination combined with viral prophylaxis reduces the risk of wheeze, asthma, and lower respiratory tract infections (LRTIs).
- Nutritional interventions during pregnancy and early probiotics/microbiota modulation showed no significant impact on asthma or wheeze outcomes.
- Exposure to allergens, environmental pollutants, and infant clinical factors increases the likelihood of developing asthma and allergic conditions.
- Long-term studies confirm that early-life risk factors have a lasting impact on respiratory and allergic disease development.
- Publication bias was noted in studies on viral prophylaxis, respiratory infections, and allergen exposure.