Post-traumatic headache two to four months after mild traumatic brain injury: A description of phenotypes and treatment patterns - PubMed
3 days ago
- #mild traumatic brain injury
- #post-traumatic headache
- #migraine-like phenotype
- Study focuses on post-traumatic headache (PTH) 2-4 months after mild traumatic brain injury (mTBI).
- 218 individuals aged 18-60 with moderate to severe PTH and high post-concussion symptom burden were analyzed.
- 62% had acute PTH, 38% persistent PTH; 88% exhibited migraine-like/probable migraine-like phenotypes.
- 78% reported headache frequency ≥15 days/month; 94% had moderate/severe intensity; 85% described pressing/tightening quality.
- No significant differences in phenotype distribution between acute/persistent PTH or sexes.
- 88% used non-opioid analgesics (81% continued use), 52% reported lack of efficacy; triptans used by only 4%.
- Preventive medication used by 7%, all reported lack of efficacy but continued treatment.
- 27% had probable medication overuse headache; 33% tried ≥2 non-pharmacological treatments.
- Limited efficacy of pharmacological/non-pharmacological treatments observed; low adherence to guideline-recommended therapies.
- High healthcare-seeking behavior noted; calls for disease-specific PTH treatment approaches.