Ferroptosis of smooth muscle cells in vascular diseases: from basic principles to clinical translation - PubMed
12 hours ago
- #smooth muscle cells
- #vascular diseases
- #ferroptosis
- Ferroptosis is an iron-dependent form of regulated cell death involving lipid hydroperoxides.
- Vascular smooth muscle cells (VSMCs) are crucial for vascular homeostasis and remodeling.
- VSMC ferroptosis is implicated in various vascular diseases, including atherosclerosis, hypertension, and aortic aneurysm.
- Understanding VSMC ferroptosis mechanisms may offer new therapeutic targets for vascular diseases.
- The review highlights current evidence and potential treatments targeting ferroptosis in vascular pathologies.