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Prolonged Dual Hypothermic Oxygenated Machine Perfusion for Daytime Liver Transplant - PubMed

5 hours ago
  • #liver transplant
  • #machine perfusion
  • #daytime surgery
  • Prolonged dual hypothermic oxygenated machine perfusion (DHOPE-PRO) increased the percentage of daytime liver transplants from 48.4% to 84.6%.
  • DHOPE-PRO extended median preservation duration from 2.1 to 10.2 hours, with total preservation up to 31.4 hours.
  • The use of DHOPE-PRO showed no association with increased postoperative complications, such as acute kidney injury.
  • One-year patient and graft survival rates remained similar to those with short-DHOPE, with survival exceeding 90% across subgroups.
  • The study suggests DHOPE-PRO facilitates daytime transplant scheduling without compromising clinical outcomes.