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The oral microbiome as a regulatory hub for systemic health: a systematic review of mechanistic links and clinical implications - PubMed

5 days ago
  • #dysbiosis
  • #systemic health
  • #oral microbiome
  • The oral microbiome plays a crucial role in both oral and systemic health.
  • Oral dysbiosis is linked to systemic diseases through mechanisms like pathogen dissemination, inflammation, and molecular mimicry.
  • Associations exist between oral microbiome changes and diseases such as cardiovascular disease, diabetes, Alzheimer's, and cancer.
  • Non-invasive oral microbiome biomarkers show promise for early disease detection and monitoring.
  • Emerging interventions like probiotics and bacteriophage therapy may help restore oral microbiome balance and improve health outcomes.
  • Integrating oral microbiome assessment into disease management could enhance treatment, but more standardized methods and causal evidence are needed.