Complete Blood Count-Derived Inflammation Indices to Predict 3-Year All-Cause Mortality in Patients With Diabetes and Acute Myocardial Infarction in Critical Care: Retrospective Cohort Study With Sing
7 hours ago
- #acute myocardial infarction
- #inflammation indices
- #diabetes
- Inflammation plays a key role in diabetes and acute myocardial infarction (AMI) progression.
- Study aims to predict 3-year all-cause mortality in diabetic AMI patients using inflammation indices.
- Analyzed 833 patients from MIMIC-IV database and 166 from Zhongnan Hospital.
- Five inflammation indices (LMR, NLR, NPR, PLR, PIV) were evaluated for mortality association.
- LMR was protective (HR 0.44), while NLR (HR 1.78) and PIV (HR 1.59) increased mortality risk.
- Kaplan-Meier analysis showed mortality trends with varying quartiles of inflammation indices.
- Predictive model achieved AUC of 0.803 (internal) and 0.781 (external validation).
- Model is cost-effective and useful for resource-limited settings but needs multicenter validation.