Woman with three deadly diseases has 'remarkable' recovery after cell therapy

4 hours ago

A woman with three life-threatening autoimmune diseases returned to near-normal life after CAR-T cell therapy.
She had autoimmune haemolytic anaemia, immune thrombocytopenia, and antiphospholipid syndrome, all resistant to nine previous treatments.
CAR-T therapy, typically used for cancers, targeted rogue B-cells causing her conditions, leading to remission within weeks.
After therapy, she stopped needing daily blood transfusions, improved in all diseases, and has been in treatment-free remission for 14 months.
The treatment may have reset her immune system, as her B-cells returned healthy, though long-term durability needs clinical trials.
Experts note the potential for CAR-T therapy in other autoimmune diseases, with trials underway for lupus, MS, and others.

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