Human skin DNA fertilised to make embryo for first time
7 hours ago
- #embryo-research
- #genetic-engineering
- #infertility-solutions
- US scientists created early-stage human embryos using DNA from skin cells and sperm for the first time.
- The technique could help overcome infertility due to age or disease, using almost any body cell as a starting point.
- It may enable same-sex couples to have genetically related children.
- The method requires significant refinement, potentially taking a decade before clinical use.
- The process involves transferring a skin cell nucleus into a donor egg stripped of its genetic material.
- The egg must discard half its chromosomes, a process termed 'mitomeiosis'.
- 82 functional eggs were created, some progressing to early embryo stages, but none developed beyond six days.
- The technique has limitations, including random chromosome discarding and a low success rate (~9%).
- Experts emphasize the need for public dialogue and robust governance to build trust in such advancements.
- Potential applications include helping older women, men with low sperm counts, and cancer survivors who are infertile.