The Role of Magnetic Resonance Spectroscopy (MRS), Diffusion-Tensor-Imaging (DTI) and Structural MRI in the Alzheimer's Disease and Mild Cognitive Impairment Diagnosis: A Review - PubMed
5 hours ago
- #Alzheimer's disease
- #MRI techniques
- #early diagnosis
- Alzheimer's disease (AD) is a common neurological disorder affecting older adults, with cases projected to rise significantly in the US by 2060.
- Early diagnosis techniques are crucial for timely treatment and prevention of full-blown disease consequences.
- The review evaluates the diagnostic value of multimodal MRI techniques (MRS, DTI, structural MRI) for detecting early metabolic, microstructural, and anatomical changes in AD.
- Key vulnerable regions identified include the posterior cingulate cortex (PCC) and hippocampus.
- Multimodal imaging could help in early AD detection, predicting progression from mild cognitive impairment (MCI), and improving patient monitoring.
- Standardized multimodal MRI protocols may support future differential diagnostic methods for dementias.