Traditional cardiovascular risk factors and their association with atherosclerotic cardiovascular disease in homozygous familial hypercholesterolemia: A cross-sectional analysis from the HICC registry
8 hours ago
- #familial hypercholesterolemia
- #hypertension
- #cardiovascular disease
- Study examines prevalence of traditional cardiovascular risk factors in homozygous familial hypercholesterolemia (HoFH) patients and their association with coronary artery disease.
- Among 912 HoFH patients, hypertension prevalence was 16.5%, diabetes 3.8%, smoking 8.2%, overweight 25.4%, and obesity 17.6%.
- Risk factors were more common in older patients, those from high-income countries, and those achieving lower LDL-C levels.
- After propensity score matching, hypertension was significantly associated with CAD (OR 1.85), while diabetes, smoking, and obesity were not.
- Results highlight the importance of proactive hypertension management alongside intensive lipid-lowering therapy in HoFH.