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Thrombophilia Screening in Young Patients With Cryptogenic Ischemic Stroke - PubMed

4 hours ago
  • #ischemic stroke
  • #thrombophilia
  • #young adults
  • The study investigates thrombophilia screening in young patients (18-49 years) with cryptogenic ischemic stroke (CIS).
  • Thrombophilia abnormalities were found in 37.1% of patients at baseline, with high-risk thrombophilia in 5.2%.
  • Persistent thrombophilia abnormalities were observed in 8.1% of patients, with similar rates in men and women.
  • Factors associated with thrombophilia deviations included physical inactivity, history of venous thromboembolism, low HDL-cholesterol, and low hemoglobin.
  • Anticoagulation was more frequently initiated in patients with abnormal thrombophilia results (50.0% vs. 35.7% without abnormalities).
  • Screening may be beneficial for young CIS patients with specific risk factors like venous thromboembolism, physical inactivity, or low hemoglobin/HDL-cholesterol.