Deep learning-based semantic matching of cis-regulatory DNA sequences facilitates the prediction of gene function - PubMed
3 days ago
- #deep learning
- #cis-regulatory sequences
- #gene function prediction
- Deep learning model PhytoBabel captures semantic similarity in cis-regulatory DNA sequences.
- PhytoBabel trained on orthologous sequences from 15 angiosperms learns gene expression patterns and conserved sequences.
- Identifies semantically similar but evolutionarily unrelated cis-regulatory sequences for novel gene discovery.
- Successfully predicted somatic embryogenesis-related morphogenic regulators in maize using Arabidopsis data.
- Bridges cis-regulatory sequence semantics to gene function prediction in reverse genetics.