Intravascular Imaging- vs Angiography-Guided Complex PCI: 5-Year Outcomes From a Randomized Trial - PubMed
9 hours ago
- #PCI
- #coronary artery disease
- #intravascular imaging
- Intravascular imaging-guided PCI showed better long-term outcomes compared to angiography-guided PCI for complex coronary artery lesions.
- The primary endpoint (cardiac death, target vessel-related myocardial infarction, or clinically driven target vessel revascularization) occurred in 10.5% of imaging-guided PCI patients vs. 14.9% in angiography-guided PCI patients (HR: 0.68; P = 0.009).
- Cardiac death or target vessel-related myocardial infarction was lower in the imaging-guided group (7.6% vs. 10.7%).
- Clinically driven target vessel revascularization was also lower in the imaging-guided group (4.4% vs. 6.2%).
- Definite stent thrombosis was rare but more frequent in the angiography-guided group (0.1% vs. 0.7%).
- No significant differences in procedure-related safety events were observed between the two groups.
- The study was a prospective, multicenter, open-label superiority trial conducted in South Korea with 1,639 patients randomized (2:1 ratio).