Move over, AlphaFold: open-source model predicts shape of 1B proteins
5 hours ago
- #Bioinformatics
- #Protein Structure
- #Artificial Intelligence
- ESM Atlas released with over 1 billion predicted protein structures and 6.8 billion sequences using AI tool ESMFold2.
- ESMFold2 outperforms AlphaFold3 in predicting protein complexes, including antibody-antigen interactions, and is fully open source.
- Atlas includes metagenomic sequences from environments like soil and ocean, revealing new biological connections, such as similarities between CRISPR proteins and a fungal gene-editing protein.