Aberrant SOD1 aggregates in skeletal muscle target fibers in amyotrophic lateral sclerosis - PubMed
4 hours ago
- #muscle pathology
- #ALS
- #SOD1
- Aberrant SOD1 aggregates found in skeletal muscle target fibers in ALS.
- Study approved by Peking University First Hospital Ethics Committee (2024-248-003).
- Patients provided informed consent for biopsy and research use of tissue/data.
- Samples and data were de-identified before analysis.
- References discuss SOD1 misfolding, STIM1 accumulation, and TDP-43 in ALS pathology.