Beyond the Gut: A Case Report of Antibiotic-Induced Dysbiosis as a Hidden Cause of Chronic Insomnia - PubMed
4 hours ago
- #gut-brain axis
- #probiotics
- #chronic insomnia
- Chronic insomnia may be linked to gut dysbiosis caused by prolonged antibiotic use.
- A case study of a 40-year-old man with leukemia showed severe insomnia unresponsive to traditional treatments after extensive antibiotic exposure.
- Gut dysbiosis was identified with a low Firmicutes/Bacteroidetes ratio and overgrowth of harmful bacteria like Streptococcus and Klebsiella.
- Targeted interventions including probiotics, fermented foods, and dietary changes improved sleep and overall health without medication.
- The microbiome-gut-brain axis plays a critical role in regulating sleep and neurotransmitter pathways.
- Clinicians should consider gut microbiome assessment in cases of persistent insomnia, especially with a history of antibiotic use.